Disc Medicine planning trial of iron overload treatment for sickle...

Disc Medicine to Launch Trial for Iron Overload Treatment in Sickle Cell Disease

Disc Medicine is planning to launch a clinical trial by the end of the year to test DISC-3405, its treatment candidate for iron overload, in people with sickle cell disease (SCD).

Iron overload is a common problem in SCD due to frequent blood transfusions.

“We’re … excited about the progress across our iron homeostasis [balance] portfolio, DISC-0974 and DISC-3405, as these programs will be important drivers of Disc’s future growth,”

said John Quisel, PhD, Disc’s CEO and president. He also stated that the company plans to initiate a Phase 1b trial of DISC-3405 in sickle cell disease by year end.

Author's summary: Disc Medicine plans to test iron overload treatment.

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Sickle Cell Disease News Sickle Cell Disease News — 2025-10-28

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