Psilocybin therapy may ease fear and depression in cancer patients

Psilocybin Therapy May Ease Fear and Depression in Cancer Patients

Researchers are exploring the potential of psilocybin therapy to lessen fear, anxiety, and depression in individuals with advanced cancer. Rather than being used recreationally, psychedelics are being tested as tools to help patients who face mortality and find little relief in traditional therapies.

Clinical Trials at Leading Universities

Scientists from the University of Colorado Anschutz Medical Campus and New York University have launched a large-scale clinical trial of psilocybin treatment. Their goal is to support patients with advanced cancer as they deal with emotional distress and the fear of dying.

Scientific Background

This new study builds upon decades of smaller but notable research showing that a single guided psilocybin session can reduce existential distress in people facing life-threatening illnesses. The current trial expands the scope with stricter controls, standardized dosing, professional guidance, and long-term follow-up.

Expert Insights

“Antidepressant medications, like SSRIs, often have no benefit or very little benefit for these patients,” said Dr. Stacy Fischer, a geriatric and palliative care specialist at UCHealth University of Colorado Hospital.

Dr. Fischer, along with psychologist Jim Grigsby from CU Denver, emphasized that many patients with advanced cancer find limited relief in existing pharmacological options, prompting the need for innovative approaches like psilocybin therapy.

Summary

Pioneering research into psilocybin therapy offers fresh hope for easing depression and fear in cancer patients where traditional treatments fall short.

Earth.com — 2025-11-02