High Disease Perception in Brain Predicts TNF Inhibitor Response in Rheumatoid Arthritis
Research published in The Lancet Rheumatology reveals that high central nervous system pain activation, measured by functional MRI, predicts treatment response to TNF inhibitors in patients with rheumatoid arthritis.
This study addresses a new concept of RA, as it shows that patients with high disease perception in the brain are more likely to respond to treatment with TNF inhibition
According to Georg Schett, MD, of Friedrich-Alexander University Erlangen-Nürnberg, in Germany, this concept is significant for understanding treatment outcomes. Author's summary: Study links brain activity to treatment response.
- High central nervous system pain activation predicts treatment response
- Functional MRI measures pain activation
- TNF inhibitors used in rheumatoid arthritis treatment