High-Dose Inactivated Influenza Vaccine Linked to Lower Rates of Hospitalization in HF
Patients with heart failure who receive a high-dose inactivated influenza vaccine have a decreased risk for hospitalization.
According to a study in Circulation: Heart Failure, the high-dose inactivated influenza vaccine (HD-IIV) is associated with reduced rates of hospitalizations related to laboratory-confirmed influenza, cardiorespiratory disease, cardiovascular disease, and heart failure in patients with heart failure.
The findings are based on a prespecified exploratory analysis of the DANFLU-2 trial, conducted in Denmark over three consecutive influenza seasons from 2022 to 2025.
- The trial included individuals aged 65 years and older.
- Participants were randomly assigned to receive either HD-IIV or standard-dose inactivated influenza vaccine (SD-IIV).
No direct quote available in the text.
Author's summary: High-dose influenza vaccine reduces hospitalization risk in heart failure patients.
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